Publications 2025
Ebner, L.J.A., Karademir, D., Nötzli, S., Wögenstein, G.M., Samardzija, M., Grimm, C. (2025).
Oxygen-dependent alternative mRNA splicing and a cone-specific motor protein revealed by single-cell RNA sequencing in hypoxic retinas
Exp Eye Res. 2025, 14:6578. doi: 10.1038/s41467-023-42386-0 Govers, L.P., Grimm, C. (2025). The connection between cellular metabolism and retinal disease
Adv Exp Med Biol. 2025; 1468:267-271. doi: 10.1007/978-3-031-76550-6_44 Wögenstein, G.M., Grimm, C. (2025). Genetically encoded metabolic sensors to study retina metabolism Adv Exp Med Biol. 2025;1468:465-469. doi: 10.1007/978-3-031-76550-6_76 Merolla, M., Samardzija, M., Kostic, C., Grimm, C. (2025). Photoreceptor activation drives the expression of the immediate-early gene Egr1 in
inner retinal neurons Exp Eye Res. 2025 Aug 26:110602. doi: 10.1016/j.exer.2025.110602 Geiger, F., Heigl, T., Merolla, M., Yong, M., Wögenstein, GM., Govers, L., Tsioti, I., Fottner, A., Samardzija, M., Grimm, C. (2025). HIF1 activity drives type 3 neovascularization and retinal atrophy in a new mouse model of
age-related macular degeneration Cell Death Dis 16, 687 (2025). https://doi.org/10.1038/s41419-025-08028-7 Ebner, L.J.A., Imsand, C., Karademir, D., Peters, F., Kiessling, E., Fottner, A., Matter, C., Fajardo, D.S., Merolla, L., Wögenstein, G.M., Tsioti, I., Govers, L.P., Blaser, F., Meneau, I., Boye, S.L., Boye, S.E., Grimm, C., Samardzija, M. (2025). A novel multiplex RNAi therapy simultaneously targets Hif1a and Hif2a to defy retinal degeneration in two models of AMD Mol Ther, 2025 Sep 27:S1525-0016(25)00815-9. doi: 10.1016/j.ymthe.2025.09.044 Wögenstein, GM., Ravotto, L., Todorova, V., Meister, RM., Samardzija, M., Weber, B., Grimm, C. Biosensor imaging maps aerobic glycolysis to photoreceptors and reveals
metabolic divergence across retinal layers Submitted Merolla, L., Fottner, A., Imsand, C., Matter, C., Rowlan, J., Neitz, M., Govers, P., Samardzija, M., Grimm, C.
RNA interference to reduce Egr1 expression in rods delays retinal degeneration in
a model of retinitis pigmentosa
Submitted
Exp Eye Res. 2025, 14:6578. doi: 10.1038/s41467-023-42386-0 Govers, L.P., Grimm, C. (2025). The connection between cellular metabolism and retinal disease
Adv Exp Med Biol. 2025; 1468:267-271. doi: 10.1007/978-3-031-76550-6_44 Wögenstein, G.M., Grimm, C. (2025). Genetically encoded metabolic sensors to study retina metabolism Adv Exp Med Biol. 2025;1468:465-469. doi: 10.1007/978-3-031-76550-6_76 Merolla, M., Samardzija, M., Kostic, C., Grimm, C. (2025). Photoreceptor activation drives the expression of the immediate-early gene Egr1 in
inner retinal neurons Exp Eye Res. 2025 Aug 26:110602. doi: 10.1016/j.exer.2025.110602 Geiger, F., Heigl, T., Merolla, M., Yong, M., Wögenstein, GM., Govers, L., Tsioti, I., Fottner, A., Samardzija, M., Grimm, C. (2025). HIF1 activity drives type 3 neovascularization and retinal atrophy in a new mouse model of
age-related macular degeneration Cell Death Dis 16, 687 (2025). https://doi.org/10.1038/s41419-025-08028-7 Ebner, L.J.A., Imsand, C., Karademir, D., Peters, F., Kiessling, E., Fottner, A., Matter, C., Fajardo, D.S., Merolla, L., Wögenstein, G.M., Tsioti, I., Govers, L.P., Blaser, F., Meneau, I., Boye, S.L., Boye, S.E., Grimm, C., Samardzija, M. (2025). A novel multiplex RNAi therapy simultaneously targets Hif1a and Hif2a to defy retinal degeneration in two models of AMD Mol Ther, 2025 Sep 27:S1525-0016(25)00815-9. doi: 10.1016/j.ymthe.2025.09.044 Wögenstein, GM., Ravotto, L., Todorova, V., Meister, RM., Samardzija, M., Weber, B., Grimm, C. Biosensor imaging maps aerobic glycolysis to photoreceptors and reveals
metabolic divergence across retinal layers Submitted Merolla, L., Fottner, A., Imsand, C., Matter, C., Rowlan, J., Neitz, M., Govers, P., Samardzija, M., Grimm, C.
RNA interference to reduce Egr1 expression in rods delays retinal degeneration in
a model of retinitis pigmentosa
Submitted