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Lab for Retinal Cell Biology

Publications 2001

Seeliger M., Grimm C., Stahlberg F., Friedburg C., Jaissle G., Zrenner E., Gao H., Remé C.E., Humphries P., Hofmann F., Biel M., Fariss R.N., Redmond T.M., Wenzel A. (2001).
New views on RPE65 deficiency: The rod system is the source of vision in a mouse model of Lebers congenital amaurosis.
Nature Genetics. 29: 70-74.

Grimm C., Wenzel A., Behrens A., Hafezi F., Wagner E.F., Remé C.E. (2001).
AP–1 mediated retinal photoreceptor apoptosis is independent of the JNK-pathway.
Cell Death Differ. 8: 859-867.

Rutjes S.A., Lund E., van der Hejiden A., Grimm C., van Venrooji W.J., Pruijn G.J.M. (2001).
Identification of a novel cis–acting RNA element involved in nuclear export of hY RNAs.
RNA 7: 742-752.

Wenzel A., Grimm C., Seeliger M., Jaissle G., Hafezi F., Kretschmer R., Zrenner E., Remé C.E. (2001).
Prevention of photoreceptor apoptosis by activation of the glucocorticoid receptor.
Invest. Ophthalmol. Vis. Sci. 42: 1653-1659.

Keller C., Grimm C., Wenzel A., Hafezi F., Remé C.E. (2001).
Protective effect of halothane anesthesia on retinal light damage: inhibition of metabolic rhodopsin regeneration.
Invest. Ophthalmol. Vis. Sci. 42: 476–480.

Grimm C., Williams T.P., Wenzel A., Remé C.E. (2001).
Rhodopsin – mediated blue light damage to the retina: Effect of photoreversal of bleaching.
Invest. Ophthalmol. Vis. Sci. 42: 497–505.

Wenzel A., Remé C.E., Williams T.P., Hafezi F., Grimm C. (2001).The Rpe65 Leu450Met mutation increases retinal resistance against light–induced degeneration by slowing rhodopsin regeneration.
J. Neurosci. 21: 53–58.

Grimm C., Suter M., Wenzel A., Jäätela M., Esser P., Kociok N., Leist M., Richter C., Remé C.E. (2001).
A2E inhibits mitochondrial function, causes the release of pro–apoptotic proteins and induces apoptosis in mammalian cells.
In New insights into retinal degenerative diseases. Anderson R.E., LaVail M.M., Hollyfield J.G. (eds). Kluwer Academic / Plenum Publishers, New York. p223-233.